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Nanchangmycin

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Cat.No：IN0850 Solarbio

CAS：65101-87-3

Molecular Formula：C₄₇H₇₇NaO₁₄

Molecular Weight：889.1

Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to off-white Solid

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Product Information

CAS	65101-87-3
Name	Nanchangmycin
Molecular Formula	C₄₇H₇₇NaO₁₄
Molecular Weight	889.1
Solubility	Soluble in DMSO
Purity	≥98%
Appearance	White to off-white Solid
Storage	Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
MDL	MFCD02874368
SMILES	C[C@H]1[C@@]2(O[C@]([C@@]3([H])O[C@](O)([C@H](C)C[C@@H]3C)CO)([H])C[C@@H]2C)O[C@]([C@]4(O[C@]5(O[C@]([C@H](C)[C@@H](O)C5)([H])[C@@H](C)/C=C(C)/C([C@H](C)C[C@H](C)C([O-])=O)=O)CC4)C)([H])C[C@@H]1O[C@@]6([H])O[C@@H]([C@@H](OC)CC6)C.[Na+]
Target Point	Bacterial
Passage	Anti-infection
Background	Nanchangmycin can inhibit Gram-positive bacteria.
Biological Activity	Nanchangmycin 由 Streptomyces nanchangensis NS3226 产生的，抑制革兰氏阳性菌。Nanchangmycin 也是一种抗 Zika 病毒的广谱抗病毒药物。[1-2]
Data Literature Source	[1]. Liu T et al. Mechanism of thioesterase-catalyzed chain release in the biosynthesis of the polyether antibiotic nanchangmycin. Chem Biol. 2008 May;15(5):449-58. [2]. Rausch K，et al. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus. Cell Rep. 2017 Jan 17;18(3):804-815.
Unit	Bottle
Specification	5mg 10mg 50mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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