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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Zoledronic AcidCAS：118072-93-8
Molecular Formula：C5H10N2O7P2
Molecular Weight：272.09
Storage：Powder:2-8℃，2 years
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 118072-93-8 |
| Name | Zoledronic Acid |
| Molecular Formula | C5H10N2O7P2 |
| Molecular Weight | 272.09 |
| Solubility | Soluble in 1M NaOH ≥5mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years |
| EC | EINECS 1806241-263-5 |
| MDL | MFCD00867791 |
| SMILES | OC(CN1C=CN=C1)(P(O)(O)=O)P(O)(O)=O |
| Target Point | Osteoclast |
| Passage | Immunology&Inflammation |
| Background | Zoledronic Acid inhibits osteoclast-mediated bone resorption and has antitumor activity. |
| Biological Activity | Zoledronic Acid 是第三代含氮二磷酸盐，能够抑制破骨细胞介导的骨吸收，同时具有抗肿瘤的活性。[1-2] |
| Data Literature Source | [1]. Scheper M， et al. A novel soft-tissue in vitro model for bisphosphonate-associated osteonecrosis. ibrogenesis Tissue Repair. 2010 Apr 1; 3:6. [2]. Wang L， et al. The apoptotic effect of Zoledronic acid on the nasopharyngeal carcinoma cells via ROS mediated chloride channel activation. Clin Exp Pharmacol Physiol. 2018 Jun 8. |
| Unit | Bottle |
| Specification | 100mg 200mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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A Targeted Erythrocyte Membrane-Encapsulated Drug-Delivery System with Anti-osteosarcoma and Anti-osteolytic Effects
Click to check >>Author：Wu X; Zhang X; Feng W; Feng H; Ding Z; Zhao Q; Li
IF：10.3830
Publish_to：ACS Appl Mater Interfaces
PMID：34125517
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