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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > TG100-115CAS：677297-51-7
Molecular Formula：C18H14N6O2
Molecular Weight：346.34
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥99%
Appearance：Light yellow to yellow Solid
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| CAS | 677297-51-7 |
| Name | TG100-115 |
| Molecular Formula | C18H14N6O2 |
| Molecular Weight | 346.34 |
| Solubility | Soluble in DMSO |
| Purity | ≥99% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00008644 |
| SMILES | NC1=C(C(N=C2C3=CC(O)=CC=C3)=NC(N)=N1)N=C2C4=CC(O)=CC=C4 |
| Target Point | PI3K |
| Passage | PI3K/Akt/mTOR |
| Background | TG100-115 is a selective PI3Kγ/PI3Kδ inhibitor. |
| Biological Activity | TG100-115 是一种选择性的 PI3Kγ/PI3Kδ 抑制剂，IC50 分别为 83 和 235 nM。[1] |
| IC50 | PI3Kγ:83nM;PI3Kδ:235nM [1] |
| Data Literature Source | [1]. Doukas J，et al. Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19866-71. |
| Unit | Bottle |
| Specification | 5mg 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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