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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > DNA Damage & DNA Repai > IfosfamideCAS：3778-73-2
Molecular Formula：C7H15Cl2N2O2P
Molecular Weight：261.09
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥99%
Appearance：White to off-white Solid
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| CAS | 3778-73-2 |
| Name | Ifosfamide |
| Molecular Formula | C7H15Cl2N2O2P |
| Molecular Weight | 261.09 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥99% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 223-237-3 |
| MDL | MFCD00057374 |
| SMILES | ClCCN1P(OCCC1)(NCCCl)=O |
| InChIKey | HOMGKSMUEGBAAB-UHFFFAOYSA-N |
| InChI | InChI=1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12) |
| PubChem CID | 3690 |
| Target Point | DNA Alkylator |
| Passage | DNA Damage/DNA Repair |
| Background | Idramantone is an immune stimulant that can be used in research related to neurological diseases. |
| Biological Activity | Ifosfamide 是一种烷化剂 (DNA alkylator)，具有广谱的抗肿瘤作用。[1-3] |
| Data Literature Source | [1]. Helal M. Prenatal effects of transplacental exposure to ifosfamide in rats. Biotech Histochem. 2016 Jul; 91 (5) :357-68. [2]. Karle P， et al. Necrotic， rather than apoptotic， cell death caused by cytochrome P450-activated ifosfamide. Cancer Gene Ther. 2001 Mar; 8 (3) :220-30. [3]. Vredenburg G， et al. Activation of the anticancer drugs cyclophosphamide and ifosfamide by cytochrome P450 BM3 mutants. Toxicol Lett. 2015 Jan 5; 232 (1) :182-92 |
| Unit | Bottle |
| Specification | 100mg 200mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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