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Amisulpride

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Cat.No：IA1840 Solarbio

CAS：71675-85-9

Molecular Formula：C₁₇H₂₇N₃O₄S

Molecular Weight：369.48

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to off-white Solid

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Product Information

CAS	71675-85-9
Name	Amisulpride
Molecular Formula	C₁₇H₂₇N₃O₄S
Molecular Weight	369.48
Solubility	Soluble in DMSO
Purity	≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 275-831-7
MDL	MFCD00866691
SMILES	CCN1C(CNC(C2=CC(S(=O)(CC)=O)=C(N)C=C2OC)=O)CCC1
InChIKey	NTJOBXMMWNYJFB-UHFFFAOYSA-N
InChI	InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)
PubChem CID	2159
Target Point	Dopamine Receptor
Passage	Neuronal Signaling;GPCR & G Protein
Background	Amisulpride is a dopamine D2/D3 receptor antagonist.
Biological Activity	Amisulpride 是一种多巴胺 D2/D3 受体拮抗剂，对于人多巴胺 D2 和 D3 的 Ki 值分别为 2.8 和 3.2 nM[1-2]。
Data Literature Source	[1]. Schoemaker H，et al. Neurochemical characteristics of amisulpride，an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity. J Pharmacol Exp Ther. 1997 Jan;280(1):83-97. [2]. Pawar GR，et al. Evaluation of antidepressant like property of amisulpride per se and its comparison with fluoxetine and olanzapine using forced swimming test in albino mice. Acta Pol Pharm. 2009 May-Jun;66(3):327-31
Unit	Bottle
Specification	100mg 500mg 1g

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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