{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > YM-155CAS：781661-94-7
Molecular Formula：C20H19BrN4O3
Molecular Weight：443.29
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
Qty：
Size：
| CAS | 781661-94-7 |
| Name | YM-155 |
| Molecular Formula | C20H19BrN4O3 |
| Molecular Weight | 443.29 |
| Solubility | Soluble in Water/DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01862936 |
| SMILES | O=C1C2=C(C(C3=CC=CC=C31)=O)[N+](CC4=NC=CN=C4)=C(C)N2CCOC.[Br-] |
| Target Point | Survivin |
| Passage | Apoptosis |
| Background | YM-155 is a survivin inhibitor. |
| Biological Activity | YM-155是 survivin 抑制剂，IC50为0.54 nM。[1-3] |
| Data Literature Source | [1]. Nakahara T，et al. YM155，a novel small-molecule survivin suppressant，induces regression of established human hormone-refractory prostate tumor xenografts. Cancer Res. 2007 Sep 1;67(17):8014-21. [2]. Iisa T，et al. Radiosensitizing effect of YM155，a novel small-molecule survivin suppressant，in non-small cell lung cancer cell lines. Clin Cancer Res. 2008 Oct 15;14(20):6496-504. [3]. Guo K，et al. A combination of YM-155，a small molecule survivin inhibitor，and IL-2 potently suppresses renal cell carcinoma in murine model. Oncotarget. 2015 Aug 28;6(25):21137-47. |
| Unit | Bottle |
| Specification | 5mg 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
