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Sarsasapogenin

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Cat.No：IS1020 Solarbio

CAS：126-19-2

Molecular Formula：C₂₇H₄₄O₃

Molecular Weight：416.64

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	126-19-2
Name	Sarsasapogenin
Molecular Formula	C₂₇H₄₄O₃
Molecular Weight	416.64
Solubility	Soluble in Ethanol;Soluble in DMSO(Need ultrasonic or Water bath)
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 204-776-3
MDL	MFCD00270414
SMILES	C[C@@H]1[C@]2(OC[C@@H](C)CC2)O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC[C@]6([H])C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]31[H]
Target Point	NF-kB
Passage	NF-κB
Background	Sarsasapogenin is a steroid saponin with anti-diabetes， anti-oxidation， anti-cancer and anti-inflammatory activities.
Biological Activity	Sarsasapogenin 是从中草药知母中分离到的甾体皂苷元，具有抗糖尿病、抗氧化、抗癌、抗炎等多种功效。[1-3]
Data Literature Source	[1]. Shen S，et al. Sarsasapogenin induces apoptosis via the reactive oxygen species-mediated mitochondrial pathway and ER stress pathway in HeLa cells. Biochem Biophys Res Commun. 2013 Oct 26. [2]. Feng B，et al. Sarsasapogenin reverses depressive-like behaviors and nicotinic acetylcholine receptors induced by olfactory bulbectomy. Neurosci Lett. 2017 Feb 3;639:173-178. [3]. Lim SM，et al. Timosaponin AIII and its metabolite sarsasapogenin ameliorate colitis in mice by inhibiting NF-κB and MAPK activation and restoring Th17/Treg cell balance. Int Immunopharmacol. 2015 Apr;25(2):493-503
Unit	Bottle
Specification	5mg 10mg 20mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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