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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > ElesclomolCAS：488832-69-5
Molecular Formula：C19H20N4O2S2
Molecular Weight：400.52
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 488832-69-5 |
| Name | Elesclomol |
| Molecular Formula | C19H20N4O2S2 |
| Molecular Weight | 400.52 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD12911784 |
| SMILES | S=C(C1=CC=CC=C1)N(NC(CC(NN(C(C2=CC=CC=C2)=S)C)=O)=O)C |
| Target Point | ROS;cuproptosis |
| Passage | Immunology & Inflammation;Apoptosis |
| Background | Elesclomol is a oxidative stress inducer that can induce apoptosis of cancer cells. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol is an effective copper ion carrier that can promote copper death (cuproptosis). |
| Data Literature Source | [1]. Kirshner JR，et al. Elesclomol induces cancer cell apoptosis through oxidative stress. Mol Cancer Ther. 2008 Aug;7(8):2319-27. [2]. Bair JS，et al. Chemistry and biology of deoxynyboquinone，a potent inducer of cancer cell death. J Am Chem Soc. 2010 Apr 21;132(15):5469-7 [3]. Blackman RK，et al. Mitochondrial electron transport is the cellular target of the oncology drug elesclomol. PLoS One. 2012;7(1):e29798. [4]. Gehrmann M. Drug evaluation: STA-4783--enhancing taxane efficacy by induction of Hsp70. Curr Opin Investig Drugs. 2006 Jun;7(6):574-80 |
| Unit | Bottle |
| Specification | 2mg 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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