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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > JAK/STAT > VitexicarpinCAS：479-91-4
Molecular Formula：C19H18O8
Molecular Weight：374.34
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 479-91-4 |
| Name | Vitexicarpin |
| Molecular Formula | C19H18O8 |
| Molecular Weight | 374.34 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00210481 |
| SMILES | O=C1C(OC)=C(C2=CC=C(OC)C(O)=C2)OC3=CC(OC)=C(OC)C(O)=C13 |
| Target Point | STAT3 |
| Passage | JAK/STAT Signaling |
| Background | Casticin can inhibit the activation of STAT3. |
| Biological Activity | Casticin 具有抗有丝分裂和抗炎活性。Casticin 能够抑制 STAT3 的活化[1-3]。 |
| Data Literature Source | [1]. Kobayakawa J，et al. G2-M arrest and antimitotic activity mediated by casticin，a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.). Cancer Lett. 2004 May 10;208(1):59-64. [2]. Zhou L，et al. Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGF-β/Smad signaling pathway. Oncotarget. 2017 Apr 27;8(34):56267-56280. [3]. Lee JH，et al. Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade. J Cell Biochem. 2018 Dec 5 |
| Unit | Piece |
| Specification | 5mg 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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