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Procyanidin B1

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Cat.No：IP1080 Solarbio

CAS：20315-25-7

Molecular Formula：C₃₀H₂₆O₁₂

Molecular Weight：578.52

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to brown Solid

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Product Information

CAS	20315-25-7
Name	Procyanidin B1
Molecular Formula	C₃₀H₂₆O₁₂
Molecular Weight	578.52
Solubility	Soluble in DMSO ≥10mg/mL
Purity	HPLC≥98%
Appearance	White to brown Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
MDL	MFCD01861512
SMILES	O[C@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3[C@@H]1C4=C5C(C[C@H](O)[C@@H](C6=CC=C(O)C(O)=C6)O5)=C(O)C=C4O
Target Point	Toll-like Receptor (TLR)
Passage	Immunology & Inflammation
Background	It is a polyphenolic flavonoid that binds to the TLR4/MD-2 complex and has anti-inflammatory activity.
Biological Activity	Procyanidin B1 是一种多酚类黄酮物质，存在于常见的水果中，能够与 TLR4/MD-2 复合体结合，具有抗炎活性。[1-3]
Data Literature Source	[1]. Xing J， et al. Anti-inflammatory effect of procyanidin B1 on LPS-treated THP1 cells via interaction with the TLR4-MD-2 heterodimer and p38 MAPK and NF-κB signaling. Mol Cell Biochem. 2015 Sep; 407 (1-2) :89-95. [2]. Kanno H， et al. Protective effects of glycycoumarin and procyanidin B1， active components of traditional Japanese medicine yokukansan， on amyloid β oligomer-induced neuronal death. J Ethnopharmacol. 2015 Jan 15; 159:122-8. [3]. Shimada T， et al. Flavangenol (pine bark extract) and its major component procyanidin B1 enhance fatty acid oxidation in fat-loaded models. Eur J Pharmacol. 2012 Feb 29; 677 (1-3) :147-53.
Unit	Piece
Specification	5mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.