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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > FarrerolCAS：24211-30-1
Molecular Formula：C17H16O5
Molecular Weight：300.31
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 24211-30-1 |
| Name | Farrerol |
| Molecular Formula | C17H16O5 |
| Molecular Weight | 300.31 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 246-080-2 |
| MDL | MFCD00017315 |
| SMILES | CC1=C(O)C(C)=C2OC(CC(=O)C2=C1O)C1=CC=C(O)C=C1 |
| Target Point | Others |
| Passage | Others |
| Background | Farrerol is a bioactive component of Rhododendron with multiple antioxidant, anti-inflammatory, antitumor, neuroprotective and hepatoprotective activities. |
| Biological Activity | Farrerol 是杜鹃花的一种生物活性成分，具有抗氧化、抗炎、抗肿瘤、神经保护和肝保护等多种作用[1-6]。 |
| Data Literature Source | [1]. Ran X，et al. Farrerol Ameliorates TNBS-Induced Colonic Inflammation by Inhibiting ERK1/2，JNK1/2，and NF-κB Signaling Pathway. Int J Mol Sci. 2018 Jul 13;19(7). [2]. Cui B，et al. Farrerol attenuates β-amyloid-induced oxidative stress and inflammation through Nrf2/Keap1 pathway in a microglia cell line. Biomed Pharmacother. 2019 Jan;109:112-119. [3]. Dai F，et al. Farrerol inhibited angiogenesis through Akt/mTOR，Erk and Jak2/Stat3 signal pathway. Phytomedicine. 2016 Jun 15;23(7):686-93. [4]. Li B，et al. Farrerol overcomes the invasiveness of lung squamous cell carcinoma cells by regulating the expression of inducers of epithelial mesenchymal transition. Microb Pathog. 2019 Jun;131:277. [5]. Li Y，et al. Farrerol protects dopaminergic neurons in a rat model of lipopolysaccharide-induced Parkinson's disease by suppressing the activation of the AKT and NF-κB signaling pathways. Int Immunopharmacol. 2019 Oct;75:105739. [6]. Wang L，et al. Farrerol Ameliorates APAP-induced Hepatotoxicity via Activation of Nrf2 and Autophagy. Int J Biol Sci. 2019 Jan 29;15(4):788-799. |
| Unit | Piece |
| Specification | 5mg 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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