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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > 1-DeoxynojirimycinCAS：19130-96-2
Molecular Formula：C6H13NO4
Molecular Weight：163.17
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 19130-96-2 |
| Name | 1-Deoxynojirimycin |
| Molecular Formula | C6H13NO4 |
| Molecular Weight | 163.17 |
| Solubility | Soluble in Water |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 606-239-2 |
| MDL | MFCD00063474 |
| SMILES | O[C@@H]1[C@@H](CO)NC[C@H](O)[C@H]1O |
| InChIKey | LXBIFEVIBLOUGU-JGWLITMVSA-N |
| InChI | InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 |
| PubChem CID | 29435 |
| Target Point | α-glucosidase |
| Passage | Metabolic Enzyme&Protease |
| Background | It is a potent α-glucosidase inhibitor. |
| Biological Activity | 1-Deoxynojirimycin (Duvoglustat) is a potent and orally active α-glucosidase inhibitor. 1-Deoxynojirimycin suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin possesses antihyperglycemic, anti-obesity, and antiviral features[1][2]. |
| Data Literature Source | [1]. Gao K，et al. 1-Deoxynojirimycin: Occurrence，Extraction，Chemistry，Oral Pharmacokinetics，Biological Activities and In Silico Target Fishing. Molecules. 2016 Nov 23;21(11). pii: E1600. [2]. Chaluntorn Vichasilp，et al. Development of high 1-deoxynojirimycin (DNJ) content mulberry tea and use of response surface methodology to optimize tea-making conditions for highest DNJ extraction. LWT - Food Science and Technology. Volume 45，Issue 2，March 2012，Pages 226-232 [3]. Liu Q，et al. 1-Deoxynojirimycin Alleviates Insulin Resistance via Activation of Insulin Signaling PI3K/AKT Pathway in Skeletal Muscle of db/db Mice. Molecules. 2015 Dec 4;20(12):21700-14. [4]. E S，Kijima R，Honma T，Yamamoto K，Hatakeyama Y，Kitano Y，Kimura T，Nakagawa K，Miyazawa T，Tsuduki T. 1-Deoxynojirimycin attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells. Exp Gerontol. 2014 Jul;55:63-9. |
| Unit | Piece |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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