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Abietic Acid

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Cat.No：IA1450 Solarbio

CAS：514-10-3

Molecular Formula：C₂₀H₃₀O₂

Molecular Weight：302.45

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	514-10-3
Name	Abietic Acid
Molecular Formula	C₂₀H₃₀O₂
Molecular Weight	302.45
Solubility	Soluble in DMSO ≥10mg/mL
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 208-178-3
MDL	MFCD03423567
SMILES	C[C@@]1(C2[C@@](CCC1)(C)[C@@]3([H])CCC(C(C)C)=CC3=CC2)C(O)=O
InChIKey	RSWGJHLUYNHPMX-ONCXSQPRSA-N
InChI	InChI=1S/C20H30O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h7,12-13,16-17H,5-6,8-11H2,1-4H3,(H,21,22)/t16-,17+,19+,20+/m0/s1
PubChem CID	10569
Target Point	5-lipoxygenase;5-LOX
Passage	Metabolic Enzyme&Protease
Background	It is a tricyclic diterpenoid oxygen-containing compound, which can inhibit lipoxygenase activity.
Biological Activity	Abietic acid (Sylvic acid，Abietate，Rosin Acid)，an abietane diterpenoid，inhibited soybean 5-lipoxygenase with an IC50 of 29.5 ± 1.29 μM.[1-2]
Data Literature Source	[1] Ulusu NN，et al. Phytother Res. 2002，16(1):88-90. [2] Hwang KH，et al. J Med Food. 2011，14(9):1052-6. [3] Takahashi N，et al. FEBS Lett. 2003，550(1-3):190-4.
Unit	Piece
Specification	5mg 10mM*1mL in DMSO 10mg 20mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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