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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > Vanillic acidCAS：121-34-6
Molecular Formula：C8H8O4
Molecular Weight：168.15
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 121-34-6 |
| Name | Vanillic acid |
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 |
| Solubility | Soluble in Ethanol/DMSO ≥20mg/mL；Soluble in Water＜2mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 204-466-8 |
| MDL | MFCD00002551 |
| SMILES | O=C(O)C1=CC=C(O)C(OC)=C1 |
| InChIKey | WKOLLVMJNQIZCI-UHFFFAOYSA-N |
| InChI | InChI=1S/C8H8O4/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4,9H,1H3,(H,10,11) |
| PubChem CID | 8468 |
| Target Point | NF-KB |
| Passage | NF-κB |
| Background | Vanillic acid inhibits NF-κB activation. Has anti-inflammatory, antibacterial and other activities. |
| Biological Activity | Vanillic acid 是一种在食用植物和水果中发现的调味剂。Vanillic acid 抑制 NF-κB 活化。具有抗炎，抗菌等活性。[1-2] |
| Data Literature Source | 1]. Calixto-Campos C，et al. Vanillic acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment，Oxidative Stress，Cytokine Production，and NFκB Activation in Mice. J Nat Prod. 2015 Aug 28;78(8):1799-808. [2]. Amin FU，et al. Vanillic acid attenuates Aβ1-42-induced oxidative stress and cognitive impairment in mice. Sci Rep. 2017 Jan 18;7:40753 |
| Unit | Piece |
| Specification | 100mg 10mM*1mL in DMSO 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Yeast-Based Whole-Cell Factory for the Ecofriendly Synthesis of Vanillylamine as a Critical Step toward Capsaicin Production
Click to check >>Author：Jinyu Zhao, Yuanyuan Li, Lijuan Yi, Genlin Zhang, Bangce Ye
IF：9.2240
Publish_to：ACS Sustainable Chemistry & Engineering
PMID：
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