Troxerutin
Cat.No:IT0880 Solarbio
CAS:7085-55-4
Molecular Formula:C33H42O19
Molecular Weight:742.68
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:Light yellow to yellow Solid
Qty:
Size:
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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > TroxerutinCAS:7085-55-4
Molecular Formula:C33H42O19
Molecular Weight:742.68
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:Light yellow to yellow Solid
Qty:
Size:
| CAS | 7085-55-4 |
| Name | Troxerutin |
| Molecular Formula | C33H42O19 |
| Molecular Weight | 742.68 |
| Solubility | Soluble in Water/DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
| EC | EINECS 230-389-4 |
| MDL | MFCD00893813 |
| SMILES | O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)O2)O)O)O)=C(C4=CC=C(OCCO)C(OCCO)=C4)OC5=CC(OCCO)=CC(O)=C15 |
| Target Point | NOD-like Receptor (NLR) |
| Passage | Immunology & Inflammation |
| Background | Troxerutin, also known as vitamin P4, is a trihydroxyethylated derivative of the natural bioflavonoid rutin, which inhibits reactive oxygen species (ROS) production and inhibits ER stress-mediated NOD activation. |
| Biological Activity | Troxerutin 也被称为维生素 P4,是天然生物类黄酮芦丁的三羟乙基化衍生物,其可抑制活性氧 (ROS) 的产生并抑制 ER 应激介导的 NOD 活化。[1-3] |
| Data Literature Source | [1]. Lim KM,et al. Analysis of changes in microRNA expression profiles in response to the troxerutin-mediated antioxidant effect in human dermal papilla cells. Mol Med Rep. 2015 Aug;12(2):2650-60. [2]. Zhang Z,et al. Troxerutin Attenuates Enhancement of Hepatic Gluconeogenesis by Inhibiting NOD Activation-Mediated Inflammation in High-Fat Diet-Treated Mice. Int J Mol Sci. 2016 Dec 25;18(1). pii: E31. [3]. Badalzadeh R,et al. Beneficial effect of troxerutin on diabetes-induced vascular damages in rat aorta: histopathological alterations and antioxidation mechanism. Int J Endocrinol Metab. 2015 Apr 30;13(2):e25969. |
| Unit | Bottle |
| Specification | 100mg 10mM*1mL in DMSO 10mM*1mL in Water 500mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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