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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Membrane Transporter & Ion Channel > Tannic acidCAS：1401-55-4
Molecular Formula：C76H52O46
Molecular Weight：1701.2
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥99%
Appearance：Off-white to Light brown Solid
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| CAS | 1401-55-4 |
| Name | Tannic acid |
| Molecular Formula | C76H52O46 |
| Molecular Weight | 1701.2 |
| Solubility | Soluble in Water/DMSO ≥10mg/mL(Need ultrasonic or Water bath) |
| Purity | ≥99% |
| Appearance | Off-white to Light brown Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 215-753-2 |
| MDL | MFCD00066397 |
| SMILES | O=C(C1=CC(OC(C2=CC(O)=C(O)C(O)=C2)=O)=C(O)C(O)=C1)OC3[C@H](OC(C4=CC(OC(C5=CC(O)=C(O)C(O)=C5)=O)=C(O)C(O)=C4)=O)[C@@H](OC(C6=CC(OC(C7=CC(O)=C(O)C(O)=C7)=O)=C(O)C(O)=C6)=O)[C@H](OC(C8=CC(OC(C9=CC(O)=C(O)C(O)=C9)=O)=C(O)C(O)=C8)=O)[C@@H](COC(C%10=CC(OC(C%11=CC(O)=C(O)C(O)=C%11)=O)=C(O)C(O)=C%10)=O)O3 |
| Target Point | Potassium Channel |
| Passage | Immunology & Inflammation;GPCR & G Protein |
| Background | Tannic acid is a novel hERG channel blocker. |
| Biological Activity | Tannic acid 是一种新型的 hERG 通道阻塞剂，其IC50 值为 3.4 μM。[1-2] |
| IC50 | 3.4μM(hERG channel)[1] |
| Data Literature Source | [1]. Xi Chu，et al. Effects of Tannic Acid，Green Tea and Red Wine on hERG Channels Expressed in HEK293 Cells. PLoS One. 2015; 10(12): e0143797. [2]. Karuppagounder V，et al. Tannic acid modulates NFκB signaling pathway and skin inflammation in NC/Nga mice through PPARγ expression. Cytokine. 2015 Dec;76(2):206-13. |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in DMSO 10mM*1mL in Water 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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