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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > Sodium cholateCAS：361-09-1
Molecular Formula：C24H39NaO5
Molecular Weight：430.55
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 361-09-1 |
| Name | Sodium cholate |
| Molecular Formula | C24H39NaO5 |
| Molecular Weight | 430.55 |
| Solubility | Soluble in Water ≥15mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 206-643-5 |
| MDL | MFCD00064138 |
| SMILES | C[C@H](CCC(O[Na])=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@@]21C |
| Target Point | Others |
| Passage | Others |
| Background | Cholic acid sodium is the major bile acid produced in the liver, usually conjugated with glycine or taurine, to aid in fat absorption and cholesterol excretion. |
| Biological Activity | Cholic acid sodium 是肝脏中产生的主要胆汁酸，通常与甘氨酸或牛磺酸缀合，有助于脂肪吸收和胆固醇排泄。[1-2] |
| Data Literature Source | [1]. Li Y，et al. Mechanism of hepatic targeting via oral administration of DSPE-PEG-Cholic acid-modified nanoliposomes. Int J Nanomedicine. 2017 Feb 28;12:1673-1684. [2]. Pan X，et al. Cholic acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice. Drug Metab Dispos. 2017 Apr;45(4):346-352 |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in Water 100mg 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Inhibition of TRAF6 improves hyperlipidemic acute pancreatitis by alleviating pyroptosis in vitro and in vivo rat models
Click to check >>Author：Wei Biwei, Su Zhou, Yang Huiying, Feng Yong, Meng Chunmei, Liang Zhihai
IF：7.1730
Publish_to：Biology Direct
PMID：37165439
Inhibition of TRAF6 improves hyperlipidemic acute pancreatitis by alleviating pyroptosis in vitro and in vivo rat models
Click to check >>Author：Wei B; Su Z; Yang H; Feng Y; Meng C; Liang Z.
IF：5.5000
Publish_to：Biology Direct
PMID：37165439
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