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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > RutaecarpineCAS：84-26-4
Molecular Formula：C18H13N3O
Molecular Weight：287.32
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 84-26-4 |
| Name | Rutaecarpine |
| Molecular Formula | C18H13N3O |
| Molecular Weight | 287.32 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 635-907-6 |
| MDL | MFCD00210551 |
| SMILES | O=C1N2C(C(NC3=C4C=CC=C3)=C4CC2)=NC5=C1C=CC=C5 |
| Target Point | COX |
| Passage | Immunology & Inflammation |
| Background | Rutaecarpine is a COX-2 inhibitor. |
| Biological Activity | Rutaecarpine, 是槐木的生物碱，是COX-2的抑制剂，其IC50值为0.28 μM.[1-3] |
| IC50 | COX-2:0.28μM( BMMC);COX-1:8.7μM(BMMC)[1-3] |
| Data Literature Source | [1]. Moon TC，et al. A new class of COX-2 inhibitor，rutaecarpine from Evodia rutaecarpa. Inflamm Res. 1999 Dec;48(12):621-5. [2]. Lee SH，et al. Progress in the studies on rutaecarpine. Molecules. 2008 Feb 6;13(2):272-300. [3]. Jeon TW，et al. Immunosuppressive effects of rutaecarpine in female BALB/c mice.Toxicol Lett. 2006 Jul 1;164(2):155-66. |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in DMSO 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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