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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > PalmatineCAS：3486-67-7
Molecular Formula：C21H22NO4+
Molecular Weight：352.41
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 3486-67-7 |
| Name | Palmatine |
| Molecular Formula | C21H22NO4+ |
| Molecular Weight | 352.41 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00221758 |
| SMILES | COC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(OC)C=C4CC3)C=C2C=C1 |
| InChIKey | QUCQEUCGKKTEBI-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H22NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,9-12H,7-8H2,1-4H3/q+1 |
| PubChem CID | 19009 |
| Target Point | Indoleamine 2,3-Dioxygenase (IDO) |
| Passage | Immunology & Inflammation;Metabolic Enzyme&Protease |
| Background | Palmatine is an irreversible IDO-1 inhibitor with multiple physiological activities. |
| Biological Activity | Palmatine 是一种口服活性的不可逆 IDO-1 抑制剂。Palmatine 可以减轻结肠损伤，预防肠道菌群失调和调节色氨酸分解代谢，从而改善DSS诱发的结肠炎。Palmatine 有潜力用于结肠炎的研究。[1] |
| Data Literature Source | [1]. Zhang XJ，et al. Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota.Pharmacol Res. 2018 Nov;137:34-46. |
| Unit | Bottle |
| Specification | 20mg 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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