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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > OxyresveratrolCAS：29700-22-9
Molecular Formula：C14H12O4
Molecular Weight：244.24
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 29700-22-9 |
| Name | Oxyresveratrol |
| Molecular Formula | C14H12O4 |
| Molecular Weight | 244.24 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 300-008-4 |
| MDL | MFCD11974969 |
| SMILES | OC1=CC=C(/C=C/C2=CC(O)=CC(O)=C2)C(O)=C1 |
| Target Point | Tyrosinase |
| Passage | Metabolic Enzyme&Protease |
| Background | Oxyresveratrol is a potent non-competitive tyrosinase inhibitor. Oxyresveratrol is effective against HSV-1， HSV-2 and varicella-zoster virus and has neuroprotective effects. Oxyresveratrol is a potent antioxidant and free radical scavenger. |
| Biological Activity | Oxyresveratrol is potent and noncompetitive tyrosinase inhibitor with an IC50 value of 1.2 μM for mushroom tyrosinase. Oxyresveratrol is effective against HSV-1， HSV-2 and varicella-zoster virus， and has neuroprotective effects.Oxyresveratrol (trans-Oxyresveratrol) is a potent naturally occurring antioxidant and free radical scavenger (IC50 of 28.9 μM against DPPH free radicals). [1-4]. |
| IC50 | 1.2μM(Mushroom tyrosinase)[2] |
| Data Literature Source | [1]. Lorenz. et al. Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: Effect on nitrosative and oxidative stress derived from microglial cells. Nitric Oxide 9(2) 64-76 (2003). [2]. Kim，Y.M.，Yun，J.，Lee，C.，et al. Oxyresveratrol and hydroxystilbene compounds. Inhbitory effect on tyrosinase and mechanism of action. J Biol Chem277(18) 16340-16344 (2002). [3]. Shaida A Andrabi et al. Oxyresveratrol (trans-2，3′，4，5′-tetrahydroxystilbene) is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia. Brain Res，2004 Aug 13，1017(1-2):98-107. [4]. Vimolmas Lipipun，et al. Topical cream-based oxyresveratrol in the treatment of cutaneous HSV-1 infection in mice. Antiviral Res. 2011 Aug;91(2):154-60. |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in DMSO 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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