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Oxymatrine

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Cat.No：IO0240 Solarbio

CAS：16837-52-8

Molecular Formula：C₁₅H₂₄N₂O₂

Molecular Weight：264.36

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	16837-52-8
Name	Oxymatrine
Molecular Formula	C₁₅H₂₄N₂O₂
Molecular Weight	264.36
Solubility	Soluble in Water/DMSO ≥10mg/mL
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 605-514-4
MDL	MFCD00210339
SMILES	O=C1CCC[C@]2([H])[C@@]3([H])CCC[N@@+]4([O-])[C@@]3([H])[C@](CCC4)([H])CN21
Target Point	TGF-beta/Smad
Passage	TGF-beta/Smad;Stem Cells
Background	Oxymatrine can inhibit iNOS expression and TGF-β/Smad pathway.
Biological Activity	Oxymatrine是来自槐属物种根部的生物碱，具有抗炎，抗纤维化和抗肿瘤的作用。能抑制iNOS表达和TGF-β/Smad通路。[1-3]
Data Literature Source	[1]. Lu ML， et al. Potential Signaling Pathways Involved in the Clinical Application of Oxymatrine. Phytother Res. 2016 Jul; 30 (7) :1104-12. [2]. Wu C， et al. Oxymatrine inhibits the proliferation of prostate cancer cells in vitro and in vivo. Mol Med Rep. 2015 Jun; 11 (6) :4129-34. [3]. Wu XL， et al. Effect of Oxymatrine on the TGFbeta-Smad signaling pathway in rats with CCl4-induced hepatic fibrosis. World J Gastroenterol. 2008 Apr 7; 14 (13) :2100-5
Unit	Bottle
Specification	100mg 10mM1mL in DMSO 10mM1mL in Water 500mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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