Isorhamnetin
Cat.No:II0410 Solarbio
CAS:480-19-3
Molecular Formula:C16H12O7
Molecular Weight:316.27
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to light yellow Solid
Qty:
Size:
{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > IsorhamnetinCAS:480-19-3
Molecular Formula:C16H12O7
Molecular Weight:316.27
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:HPLC≥98%
Appearance:White to light yellow Solid
Qty:
Size:
| CAS | 480-19-3 |
| Name | Isorhamnetin |
| Molecular Formula | C16H12O7 |
| Molecular Weight | 316.27 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to light yellow Solid |
| Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
| EC | EINECS 207-545-5 |
| MDL | MFCD00017310 |
| SMILES | O=C1C(O)=C(C2=CC=C(O)C(OC)=C2)OC3=CC(O)=CC(O)=C13 |
| Target Point | MEK;PI3K |
| Passage | MAPK;PI3K/Akt/mTOR |
| Background | Isorhamnetin is a flavonoid compound with various biological activities. Isorhamnetin has been reported to inhibit skin cancer by directly inhibiting MEK1 and PI3K. |
| Biological Activity | Isorhamnetin 是类黄酮化合物。Isorhamnetin 可通过直接抑制 MEK1 和 PI3K 来抑制皮肤癌。[1-2] |
| Data Literature Source | [1]. Kim JE, et al. Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3-K. Cancer Prev Res (Phila) . 2011 Apr; 4 (4) :582-91. [2]. Hu S, et al. Isorhamnetin inhibits cell proliferation and induces apoptosis in breast cancer via Akt and mitogen activated protein kinase kinase signaling pathways. Mol Med Rep. 2015 Nov; 12 (5) :6745-51. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg 20mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
In Vitro Effect of Flavonoids on Basophils Degranulation and Intestinal Epithelial Barrier Damage Induced by ω-5 Gliadin-Derived Peptide
Click to check >>Author:Wu S; Zhang R; Liu Y; Gao J; Wu Y; Tu C; Chen H; Y
IF:5.2000
Publish_to:Foods
PMID:36496664
Manual Download