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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Membrane Transporter & Ion Channel > 8-GingerolCAS：23513-08-8
Molecular Formula：C19H30O4
Molecular Weight：322.44
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow waxy Solid
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| CAS | 23513-08-8 |
| Name | 8-Gingerol |
| Molecular Formula | C19H30O4 |
| Molecular Weight | 322.44 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to yellow waxy Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00877794 |
| SMILES | CCCCCCC[C@H](O)CC(CCC1=CC=C(O)C(OC)=C1)=O |
| Target Point | TRP Channel |
| Passage | Membrane Transporter&Ion Channel;Neuronal Signaling |
| Background | 8-Gingerol activates TRPV1 and inhibits COX-2. |
| Biological Activity | 8-Gingerol， found in the rhizomes of ginger (Z. officinale) with oral bioavailability， activates TRPV1， with an EC50 of 5.0 μM. 8-Gingerol inhibits COX-2， and inhibits the growth of H. pylori in vitro[1-2]. |
| Data Literature Source | [1]. Dedov，V.N.，et al. Gingerols: a novel class of vanilloid receptor (VR1) agonists. Br. J. Pharmacol. 137(6)，793-798 (2002). [2]. Chrubasik，S.，et al. Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles. Phytomedicine 12(9)，684-701 (2005). |
| Unit | Bottle |
| Specification | 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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