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Forsythoside B

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Cat.No：IF0300 Solarbio

CAS：81525-13-5

Molecular Formula：C₃₄H₄₄O₁₉

Molecular Weight：756.71

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to yellow Solid

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CAS	81525-13-5
Name	Forsythoside B
Molecular Formula	C₃₄H₄₄O₁₉
Molecular Weight	756.71
Solubility	Soluble in Water/DMSO ≥100mg/mL
Purity	HPLC≥98%
Appearance	White to yellow Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 1592732-453-0
MDL	MFCD03424245
SMILES	OC1=C(O)C=C(/C=C/C(O[C@H]2[C@H](O[C@]3([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](O)[C@H](OCCC4=CC=C(O)C(O)=C4)O[C@@H]2CO[C@H]5[C@H](O)[C@](CO)(O)CO5)=O)C=C1
Target Point	TNF Receptor
Passage	Apoptosis
Background	It inhibits TNF-alpha, IL-6, IκB, and modulates NF-κB.
Biological Activity	Forsythoside B是传统中药植物独一味的叶子中分离的苯乙醇苷。独一味可用于治疗炎症疾病和促进血液循环。Forsythoside B 可抑制 TNF-alpha，IL-6，IκB，调节 NF-κB。[1-3]
Data Literature Source	[1]. Jiang WL，et al. Forsythoside B protects against experimental sepsis by modulating inflammatory factors. Phytother Res. 2012 Jul;26(7):981-7. [2]. Jiang WL，et al. Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury. Eur J Pharmacol. 2010 Aug 25;640(1-3):75-81. [3]. Jiang WL，et al. Cardioprotection with forsythoside B in rat myocardial ischemia-reperfusion injury: relation to inflammation response. Phytomedicine. 2010 Jul;17(8-9):635-9
Unit	Bottle
Specification	5mg 10mg 10mM*1mL in DMSO 20mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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