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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > Ferulic acidCAS：1135-24-6
Molecular Formula：C10H10O4
Molecular Weight：194.19
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Off-white to yellow Solid
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| CAS | 1135-24-6 |
| Name | Ferulic acid |
| Molecular Formula | C10H10O4 |
| Molecular Weight | 194.19 |
| Solubility | Soluble in DMSO ≥10mg/mL;Soluble in Ethanol ≥25mg/mL |
| Purity | HPLC≥98% |
| Appearance | Off-white to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 208-679-7 |
| MDL | MFCD00004400 |
| SMILES | O=C(O)/C=C/C1=CC=C(O)C(OC)=C1 |
| Target Point | FGFR |
| Passage | Angiogenesis; Protein Tyrosine Kinase/RTK |
| Background | Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor. |
| Biological Activity | Ferulic acid 是一种新型的成纤维细胞生长因子受体 1 (FGFR1) 抑制剂, 对于 FGFR1 和 FGFR2 的 IC50值分别为 3.78 and 12.5 μM。[1-2] |
| Data Literature Source | [1]. Yang GW，et al. Ferulic Acid Exerts Anti-Angiogenic and Anti-Tumor Activity by Targeting Fibroblast Growth Factor Receptor 1-Mediated Angiogenesis. Int J Mol Sci. 2015 Oct 12;16(10):24011-31. [2]. Zeni AL，et al. Ferulic acid exerts antidepressant-like effect in the tail suspension test in mice: evidence for the involvement of the serotonergic system. Eur J Pharmacol. 2012 Mar 15;679(1-3):68-74. |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in DMSO 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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