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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > (+)-CatechinCAS：154-23-4
Molecular Formula：C15H14O6
Molecular Weight：290.27
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellowish brown Solid
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| CAS | 154-23-4 |
| Name | (+)-Catechin |
| Molecular Formula | C15H14O6 |
| Molecular Weight | 290.27 |
| Solubility | Soluble in DMSO/Ethanol ≥5mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to yellowish brown Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 205-825-1 |
| MDL | MFCD00075649 |
| SMILES | O[C@@H]1[C@@H](C2=CC(O)=C(O)C=C2)OC3=CC(O)=CC(O)=C3C1 |
| InChIKey | PFTAWBLQPZVEMU-DZGCQCFKSA-N |
| InChI | InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m0/s1 |
| PubChem CID | 9064 |
| Target Point | COX-1 |
| Passage | Immunology & Inflammation |
| Background | (+)-Catechin is a phenolic antioxidant， can inhibit cyclooxygenase-1 (COX-1)， has anti-tumor， antioxidant， antibacterial and other biological activities. |
| Biological Activity | Catechin 抑制环加氧酶-1 (COX-1) , IC50 为 1.4 μM。[1] |
| IC50 | COX-1:1.4μM [1] |
| Data Literature Source | [1]. Waffo-Téguo P，et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9. [2]. Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167. [3]. Cheruku SP，et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70(1):245-259. |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Gegentana, et al. J Ethnopharmacol. 2020 Aug 10;258:112886.
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