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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > Baccatin ⅢCAS：27548-93-2
Molecular Formula：C31H38O11
Molecular Weight：586.63
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 27548-93-2 |
| Name | Baccatin Ⅲ |
| Molecular Formula | C31H38O11 |
| Molecular Weight | 586.63 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00153921 |
| SMILES | O=C1[C@H](OC(C)=O)C(C2(C)C)=C(C)[C@@H](O)C[C@@]2(O)[C@@H](OC(C3=CC=CC=C3)=O)[C@@]4([H])[C@@]1(C)[C@@H](O)C[C@@]5([H])OC[C@]54OC(C)=O |
| InChIKey | OVMSOCFBDVBLFW-VHLOTGQHSA-N |
| InChI | InChI=1S/C31H38O11/c1-15-19(34)13-31(38)26(41-27(37)18-10-8-7-9-11-18)24-29(6,20(35)12-21-30(24,14-39-21)42-17(3)33)25(36)23(40-16(2)32)22(15)28(31,4)5/h7-11,19-21,23-24,26,34-35,38H,12-14H2,1-6H3/t19-,20-,21+,23+,24-,26-,29+,30-,31+/m0/s1 |
| PubChem CID | 65366 |
| Target Point | Others |
| Passage | Others |
| Background | Baccatin III can delay tumor progression by reducing the accumulation of MDSCs and inhibiting their function. |
| Biological Activity | Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs[1]. |
| Data Literature Source | [1]. Lee YH，et al. Baccatin III，a precursor for the semisynthesis of paclitaxel，inhibits the accumulation and suppressive activity of myeloid-derived suppressor cells in tumor-bearing mice. Int Immunopharmacol. 2014 Aug;21(2):487-93. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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