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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > BaicaleinCAS：491-67-8
Molecular Formula：C15H10O5
Molecular Weight：270.24
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 491-67-8 |
| Name | Baicalein |
| Molecular Formula | C15H10O5 |
| Molecular Weight | 270.24 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00017459 |
| SMILES | O=C1C=C(C2=CC=CC=C2)OC3=CC(O)=C(O)C(O)=C13 |
| InChIKey | FXNFHKRTJBSTCS-UHFFFAOYSA-N |
| InChI | InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H |
| PubChem CID | 5281605 |
| Target Point | Xanthine Oxidase（XO） |
| Passage | Metabolic Enzyme&Protease |
| Background | It is a xanthine oxidase inhibitor. |
| Biological Activity | Baicalein (5,6,7-Trihydroxyflavone) 是黄嘌呤氧化酶抑制剂，其IC50值为3.12 mM.[1-4] |
| IC50 | 3.12mM(xanthine oxidase)[1] |
| Data Literature Source | [1]. Shieh DE，et al. Antioxidant and free radical scavenging effects of baicalein，baicalin and wogonin. Anticancer Res. 2000 Sep-Oct;20(5A):2861-5. [2]. Patwardhan RS，et al. Baicalein exhibits anti-inflammatory effects via inhibition of NF-κB transactivation. Biochem Pharmacol. 2016 May 15;108:75-89. [3]. Ma X，et al. Baicalein suppresses metastasis of breast cancer cells by inhibiting EMT via downregulation of SATB1 and Wnt/β-catenin pathway.Drug Des Devel Ther. 2016 Apr 18;10:1419-41. [4]. Kong EK，et al. A novel anti-fibrotic agent，baicalein，for the treatment of myocardial fibrosis in spontaneously hypertensiverats. Eur J Pharmacol. 2011 May 11;658(2-3):175-81 |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in DMSO 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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