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My CartReactivity：Mouse,Human
Application：IHC,ELISA,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：2182
Host：Rabbit
Qty：
Size：
| Name | Anti-ACSL4 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:1000-5000. IHC 1: 50-200. |
| Target | ACSL4 |
| Background | The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants. |
| Swiss Prot | O60488 |
| Gene ID | 2182 |
| Subcellular Location | Endoplasmic reticulum membrane Microsome membrane Mitochondrion outer membrane Peroxisome membrane Single-pass type III membrane protein |
| Immunogen | Recombinant protein of human ACSL4 |
| Calculated MW | 79kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Mouse Human |
| Application | IHC ELISA WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with ACSL4 antibody diluted at 1:1000
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PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells
Click to check >>Author：You J H
IF：11.1610
Publish_to：Journal of Experimental & Clinical Cancer Research
PMID：34749765
CA9 knockdown enhanced ionizing radiation-induced ferroptosis and radiosensitivity of hypoxic glioma cells
Click to check >>Author：Wenpeng Huang, Yuping He, Shuangyu Yang, Xuefei Xue, Hualong Qin, Ting Sun, Wei Yang
IF：2.6000
Publish_to：INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
PMID：37463506
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