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My CartReactivity：Mouse,Rat,Human
Application：IHC,WB,IF
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：3684
Host：Rabbit
Qty：
Size：
| Name | Anti-ITGAM Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:100-500. IHC 1:50-200. IF 1:50-200. |
| Target | ITGAM |
| Background | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Swiss Prot | P11215 |
| Gene ID | 3684 |
| Subcellular Location | Cell membrane Membrane |
| Immunogen | Recombinant protein of human ITGAM |
| Public Immunogen Range | 145-340aa |
| Calculated MW | 127kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Mouse Rat Human |
| Application | IF IHC WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with ITGAM antibody diluted at 1:1000;Lane: THP-1 U-937 Mouse lung Mouse brain Mouse spleen Rat lung.
Immunohistochemistry of paraffin-embedded human tonsil with ITGAM antibody diluted at 1:100.
Immunofluorescence analysis of TF-1 cells using ITGAM antibody diluted at 1:100.
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