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Cucurbitacin B

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Cat.No：IC0880 Solarbio

CAS：6199-67-3

Molecular Formula：C₃₂H₄₆O₈

Molecular Weight：558.7

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	6199-67-3
Name	Cucurbitacin B
Molecular Formula	C₃₂H₄₆O₈
Molecular Weight	558.7
Solubility	Soluble in DMSO
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
MDL	MFCD07778083
SMILES	O[C@H](C1)[C@@]([C@@](C)(O)C(/C=C/C(OC(C)=O)(C)C)=O)([H])[C@](C2)(C)[C@]1(C)[C@]3([H])CC=C4C(C)(C)C([C@@H](O)C[C@@]4([H])[C@]3(C)C2=O)=O
InChIKey	IXQKXEUSCPEQRD-DKRGWESNSA-N
InChI	InChI=1S/C32H46O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-13,19-22,25,34-35,39H,11,14-16H2,1-9H3/b13-12+/t19-,20+,21-,22+,25+,29+,30-,31+,32+/m1/s1
PubChem CID	5281316
Target Point	Microtubule/Tubulin
Passage	Cytoskeleton
Background	Cucurbitacin B, a tetracyclic triterpenoid compound in cucurbitacin, can interfere with microtubule polymerization and is often used in the development of long-acting anticancer compounds.
Biological Activity	Cucurbitacin B，是一种提取自葫芦科植物的氧化四环三萜类物质，用作长效的抗癌药物，可干扰微管聚合。[1]
Data Literature Source	[1] Yin D，et al. Int J Cancer. 2008，123(6)，1364-1375. [2] Wakimoto N，et al. Cancer Sci. 2008，99(9)，1793-1797. [3] Kim M. et al. Immunopharmacol Immunotoxicol. 2015，37(5)，473-480.
Unit	Bottle
Specification	5mg 10mM*1mL in DMSO 10mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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