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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > TGF-β/Smad > VerbascosideCAS：61276-17-3
Molecular Formula：C29H36O15
Molecular Weight：624.59
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 61276-17-3 |
| Name | Verbascoside |
| Molecular Formula | C29H36O15 |
| Molecular Weight | 624.59 |
| Solubility | Soluble in Water/DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00221751 |
| SMILES | O[C@@H]([C@H](OCCC1=CC(O)=C(O)C=C1)O2)[C@H]([C@@H]([C@H]2CO)OC(/C=C/C3=CC(O)=C(O)C=C3)=O)O[C@@](O[C@@H](C)[C@H](O)[C@H]4O)([H])[C@@H]4O |
| InChIKey | FBSKJMQYURKNSU-ZLSOWSIRSA-N |
| InChI | InChI=1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1 |
| PubChem CID | 5281800 |
| Target Point | PKC |
| Passage | TGF-beta/Smad;Epigenetics |
| Background | Verbascoside is an ATP-competitive PKC inhibitor. |
| Biological Activity | Verbascoside 是从 Lantana camara 中得到的糖苷类物质，为 ATP 竞争性的 PKC 抑制剂，IC50 值为 25 μM，具有抗肿瘤，抗炎，抗神经性疼痛等作用。[1-3] |
| Data Literature Source | [1]. Herbert JM，et al. Verbascoside isolated from Lantana camara，an inhibitor of protein kinase C. J Nat Prod. 1991 Nov-Dec;54(6):1595-600. [2]. Li Y，et al. Verbascoside Alleviates Atopic Dermatitis-Like Symptoms in Mice via Its Potent Anti-Inflammatory Effect. Int Arch Allergy Immunol. 2018;175(4):220-230. [3]. Amin B，et al. The Effect of Verbascoside in Neuropathic Pain Induced by Chronic Constriction Injury in Rats. Phytother Res. 2016 Jan;30(1):128-35 |
| Unit | Bottle |
| Specification | 5mg 10mg 10mM*1mL in DMSO |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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