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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Endocrinology & Hormones > TriptophenolideCAS：74285-86-2
Molecular Formula：C20H24O3
Molecular Weight：312.4
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 74285-86-2 |
| Name | Triptophenolide |
| Molecular Formula | C20H24O3 |
| Molecular Weight | 312.4 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00210567 |
| SMILES | O=C1C(CC[C@]2(C)C3=C(CC[C@]24[H])C(O)=C(C(C)C)C=C3)=C4CO1 |
| InChIKey | KPXIBWGPZSPABK-FXAWDEMLSA-N |
| InChI | InChI=1S/C20H24O3/c1-11(2)12-4-6-16-14(18(12)21)5-7-17-15-10-23-19(22)13(15)8-9-20(16,17)3/h4,6,11,17,21H,5,7-10H2,1-3H3/t17-,20+/m0/s1 |
| PubChem CID | 173273 |
| Target Point | Androgen Receptor |
| Passage | Endocrinology & Hormones |
| Background | It is a compound with anti-inflammatory activity. |
| Biological Activity | Triptophenolide is a colorless crystalline plate isolated from ethyl acetate extracts of Tripterygium wilfordii. IC50 value: Target: In vitro: Triptophenolide can remarkably inhibit the delayed type hypersensitivity (DTH) reaction induced by DNCB and BSA; and diminished the peripheral blood ANAE+lymphocytes in rats and micc. Moreover， triptophenolide can dramatically increase the amount of total serum complement and significautly decrcase the serum antibody products (1gG ) of rats and mice. The phagocytosis of perioneal exudate macrophages in mice present double effects in vitro [1]. |
| Data Literature Source | [1]. XU bin，et al. Study on polarographic catalytic wave of triptophenolide. Chinese Journal of Analysis Laboratory，2005-04 [2]. Yang Jun，et al. Studies on Antiinflammatory and Immune Effects of Triptophenolide. Chinese Traditional and Herbal Drugs，1995-01 |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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