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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > SalidrosideCAS：10338-51-9
Molecular Formula：C14H20O7
Molecular Weight：300.3
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 10338-51-9 |
| Name | Salidroside |
| Molecular Formula | C14H20O7 |
| Molecular Weight | 300.3 |
| Solubility | Soluble in Water/Ethanol ≥10mg/mL;Soluble in DMSO ≥ 3mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 695-621-2 |
| MDL | MFCD00210553 |
| SMILES | O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OCCC2=CC=C(O)C=C2 |
| InChIKey | ILRCGYURZSFMEG-RKQHYHRCSA-N |
| InChI | InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1 |
| PubChem CID | 159278 |
| Target Point | prolyl endopeptidase |
| Passage | PI3K/Akt/mTOR;Metabolic Enzyme&Protease |
| Background | It is a prolyl endopeptidase inhibitor. |
| Biological Activity | Salidroside 是一种脯氨酰内肽酶 (prolyl endopeptidase) 抑制剂。Salidroside 可通过激活 mTOR 信号缓解肿瘤恶病质小鼠模型中的恶病质症状。[1-4] |
| Data Literature Source | [1]. Fan W，et al. Prolyl endopeptidase inhibitors from the underground part of Rhodiola sachalinensis. Chem Pharm Bull (Tokyo). 2001 Apr;49(4):396-401. [2]. Chen X，et al. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activatingmTOR signalling. J Cachexia Sarcopenia Muscle. 2016 May;7(2):225-32. [3]. Wu L，et al. Salidroside Protects against MPP+-Induced Neuronal Injury through DJ-1-Nrf2 Antioxidant Pathway. Evid Based Complement Alternat Med. 2017;2017:5398542. [4]. Ju L，et al. Salidroside，A Natural Antioxidant，Improves β-Cell Survival and Function via Activating AMPK Pathway. Front Pharmacol. 2017 Oct 18;8:749. |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mM*1mL in Water 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
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Gut microbiota-based PK-PD study and molecular mechanism of Specnuezhenide in the treatment of colorectal cancer targeting carboxylesterase
Click to check >>Author：Hang Yu, Hui Xu, Xinyu Yang, Zhengwei Zhang, Jiachun Hu, Jinyue Lu, Jie Fu, Mengmeng Bu, Haojian Zhang, Zhao Zhai, Jingyue Wang, Jiandong Jiang, Yan Wang
IF：8.8000
Publish_to：Journal of Pharmaceutical Analysis
PMID：
Salidroside alleviated dextran sulfate sodium-induced colitis in mice by modulating the gut microbiota
Click to check >>Author：Jiuxi Liu, Jiapei Cai, Peng Fan, Xue Dong, Naisheng Zhang, Jiandong Tai, Yongguo Cao
IF：6.1000
Publish_to：Food & Function
PMID：37504971
Salidroside protects mice from high-fat diet-induced obesity by modulating the gut microbiota
Click to check >>Author：Jiuxi Liu, Jiapei Cai, Peng Fan, Xue Dong, Naisheng Zhang, Jiandong Tai, Yongguo Cao
IF：5.7140
Publish_to：INTERNATIONAL IMMUNOPHARMACOLOGY
PMID：37192552
Salidroside inhibits proliferation. migration and invasion of human pancreatic cancer PANC1 and SW1990 cells through the AKT and ERK signaling pathway
Click to check >>Author：Yuetong L. Shangzhu L. Qinglin H. Pingping H
IF：1.2660
Publish_to：Pharmazie
PMID：32758338
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10mM*1mL in Water 50mg这个一共是50毫克里面是用水溶的红景天苷里面的浓度是10mM*1mL噻 2023-07-20 11:25:41
Administrator您好，10mM*1mL in Water是指红景天苷浓度是10mM,溶剂是水，体积是1ml