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My CartCAS：36791-04-5
Molecular Formula：C8H12N4O5
Molecular Weight：244.21
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 36791-04-5 |
| Name | Ribavirin |
| Molecular Formula | C8H12N4O5 |
| Molecular Weight | 244.21 |
| Solubility | Soluble in Water ≥20mg/mL;Soluble in DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 636-825-3 |
| MDL | MFCD00058564 |
| SMILES | O[C@H]1[C@H](N2N=C(C(N)=O)N=C2)O[C@H](CO)[C@H]1O |
| InChIKey | IWUCXVSUMQZMFG-AFCXAGJDSA-N |
| InChI | InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1 |
| PubChem CID | 37542 |
| Target Point | HCV;RSV |
| Passage | Anti-infection |
| Background | It has broad-spectrum antiviral activity and can inhibit HCV, HIV1, RSV and other viruses. |
| Biological Activity | Ribavirin是广谱的抗病毒药，可抑制HCV，HIVl，RSV等病毒。[1-4] |
| Data Literature Source | [1]. Abdel-Hamid NM，et al. Synergistic Effects of Jerusalem Artichoke in Combination with Pegylated Interferon Alfa-2a and Ribavirin Against Hepatic Fibrosis in Rats. Asian Pac J Cancer Prev. 2016;17(4):1979-85. [2]. Refaat B，et al. The effects of pegylated interferon-α and ribavirin on liver and serum concentrations of activin-A and follistatin in normal Wistar rat: a preliminary report. BMC Res Notes. 2015 Jun 26;8:265 [3]. Savic D，et al. Ribavirin shows immunomodulatory effects on activated microglia. Immunopharmacol Immunotoxicol. 2014 Dec;36(6):433-41 [4]. Chang J，et al. Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo. Antiviral Res. 2011 Jan;89(1):26-34 |
| Unit | Bottle |
| Specification | 100mg 10mM*1mL in DMSO 200mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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