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Pepstatin

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Cat.No：IP0170 Solarbio

CAS：26305-03-3

Molecular Formula：C₃₄H₆₃N₅O₉

Molecular Weight：685.89

Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	26305-03-3
Name	Pepstatin
Molecular Formula	C₃₄H₆₃N₅O₉
Molecular Weight	685.89
Solubility	Soluble in Water ≥10mg/mL;Soluble in DMSO ≥1mg/mL(Need ultrasonic or Water bath)
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 247-600-0
MDL	MFCD00060740
SMILES	CC(C[C@H](NC([C@@H](NC([C@@H](NC(CC(C)C)=O)C(C)C)=O)C(C)C)=O)[C@@H](O)CC(N[C@@H](C)C(N[C@@H](CC(C)C)[C@@H](O)CC(O)=O)=O)=O)C
InChIKey	FAXGPCHRFPCXOO-LXTPJMTPSA-N
InChI	InChI=1S/C34H63N5O9/c1-17(2)12-23(37-33(47)31(21(9)10)39-34(48)30(20(7)8)38-27(42)14-19(5)6)25(40)15-28(43)35-22(11)32(46)36-24(13-18(3)4)26(41)16-29(44)45/h17-26,30-31,40-41H,12-16H2,1-11H3,(H,35,43)(H,36,46)(H,37,47)(H,38,42)(H,39,48)(H,44,45)/t22-,23-,24-,25-,26-,30-,31-/m0/s1
PubChem CID	5478883
Target Point	Proteasome
Passage	Metabolic Enzyme&Protease
Background	Pepstatin is a specific inhibitor of aspartic proteases.
Biological Activity	Pepstatin 是一种特异性的天冬氨酸蛋白酶 (aspartic proteases) 抑制剂，能够抑制 hemoglobin-pepsin，hemoglobin-proctase，casein-pepsin，casein-proctase，casein-acid protease 和 hemoglobin-acid protease 的活性，IC50 值分别为 4.5 nM，6.2 nM，150 nM，290 nM，520 nM 和 260 nM。[1]
Data Literature Source	[1]. Umezawa H，et al. Pepstatin，a new pepsin inhibitor produced by Actinomycetes. J Antibiot (Tokyo). 1970 May;23(5):259-62
Unit	Bottle
Specification	10mg 50mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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