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Pachymic Acid

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Cat.No：IP0010 Solarbio

CAS：29070-92-6

Molecular Formula：C₃₃H₅₂O₅

Molecular Weight：528.77

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	29070-92-6
Name	Pachymic Acid
Molecular Formula	C₃₃H₅₂O₅
Molecular Weight	528.77
Solubility	Soluble in DMSO ≥5mg/mL
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
MDL	MFCD00238657
SMILES	O[C@@H]([C@]1([H])[C@H](C(O)=O)CCC(C(C)C)=C)C[C@@]([C@]1(C)CC2)(C)C3=C2[C@]4(C)[C@](CC3)([H])C(C)(C)[C@@H](OC(C)=O)CC4
InChIKey	VDYCLYGKCGVBHN-DRCQUEPLSA-N
InChI	InChI=1S/C33H52O5/c1-19(2)20(3)10-11-22(29(36)37)28-25(35)18-33(9)24-12-13-26-30(5,6)27(38-21(4)34)15-16-31(26,7)23(24)14-17-32(28,33)8/h19,22,25-28,35H,3,10-18H2,1-2,4-9H3,(H,36,37)/t22-,25-,26+,27+,28+,31-,32-,33+/m1/s1
PubChem CID	5484385
Target Point	Akt;ERK
Passage	PI3K/Akt/mTOR;MAPK
Background	Pachymic acid is a triterpenoid that inhibits Akt and ERK signaling pathways.
Biological Activity	Pachymic acid 是一种三萜类化合物。Pachymic acid 抑制 Akt 和 ERK 信号传导途径[1-2]。
Data Literature Source	[1]. Chen Y，et al. Pachymic acid inhibits tumorigenesis in gallbladder carcinoma cells. Int J Clin Exp Med. 2015 Oct 15;8(10):17781-8. [2]. Ma J，et al. Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer cells. Cancer Cell Int. 2015 Aug 5;15:78
Unit	Bottle
Specification	1mg 5mg 10mM*1mL in DMSO

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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