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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Neochlorogenic acidCAS：906-33-2
Molecular Formula：C16H18O9
Molecular Weight：354.31
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 906-33-2 |
| Name | Neochlorogenic acid |
| Molecular Formula | C16H18O9 |
| Molecular Weight | 354.31 |
| Solubility | Soluble in DMSO ≥100mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 212-997-1 |
| MDL | MFCD10566639 |
| SMILES | O=C([C@]1(O)C[C@@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)[C@@H](O)[C@H](O)C1)O |
| InChIKey | CWVRJTMFETXNAD-NXLLHMKUSA-N |
| InChI | InChI=1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24,15(22)23)6-11(19)14(12)21/h1-5,11-12,14,17-19,21,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14+,16-/m1/s1 |
| PubChem CID | 5280633 |
| Target Point | TNF-α;NF-κB;p65;COX-2;IL-1β |
| Passage | Apoptosis;NF-κB;NF-κB;Immunology & Inflammation |
| Background | Neochlorogenic acid is a polyphenolic compound. Neochlorogenic acid inhibits TNF-α and IL-1β production. Neochlorogenic acid inhibits iNOS and COX-2 protein expression. Neochlorogenic acid also inhibits phosphorylated NF-κB p65 and p38 MAPK activation. |
| Biological Activity | Neochlorogenic acid 是在干果和其他植物中发现的一种天然多酚化合物。Neochlorogenic acid 抑制 TNF-α 和 IL-1β 产生。 Neochlorogenic acid 抑制 iNOS 和 COX-2 蛋白表达。Neochlorogenic acid 还抑制磷酸化的 NF-κB p65 和 p38 MAPK 活化。[1] |
| Data Literature Source | [1]. Kim M，et al. Neochlorogenic Acid Inhibits Lipopolysaccharide-Induced Activation and Pro-inflammatory Responses in BV2 Microglial Cells. Neurochem Res. 2015 Sep;40(9):1792-8 |
| Unit | Bottle |
| Specification | 5mg 10mM*1mL in DMSO 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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