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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > MethylthiouracilCAS：1956/4/2
Molecular Formula：C5H6N2OS
Molecular Weight：142.18
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1956/4/2 |
| Name | Methylthiouracil |
| Molecular Formula | C5H6N2OS |
| Molecular Weight | 142.18 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-252-3 |
| MDL | MFCD00006040 |
| SMILES | O=C(C=C(C)N1)NC1=S |
| InChIKey | HWGBHCRJGXAGEU-UHFFFAOYSA-N |
| InChI | InChI=1S/C5H6N2OS/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9) |
| PubChem CID | 667493 |
| Target Point | TNF-α;ERK1，2;NF-κB;IL-6 |
| Passage | Apoptosis;MAPK;NF-κB;Immunology & Inflammation |
| Background | Methylthiouracil is an antithyroid agent. Inhibits the production of TNF-α and IL-6 and the activation of NF-κB and ERK1/2. |
| Biological Activity | Methylthiouracil 是一种抗甲状腺剂。Methylthiouracil 抑制 TNF-α 和 IL-6 的产生以及 NF-κB 和 ERK1/2 的活化[1]。 |
| Data Literature Source | [1]. Ku SK， et al. Anti-inflammatory effects of methylthiouracil in vitro and in vivo. Toxicol Appl Pharmacol. 2015 Nov 1; 288 (3) :374-86 |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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