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Itraconazole

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Cat.No：II0220 Solarbio

CAS：84625-61-6

Molecular Formula：C₃₅H₃₈Cl₂N₈O₄

Molecular Weight：705.63

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to yellow Solid

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Product Information

CAS	84625-61-6
Name	Itraconazole
Molecular Formula	C₃₅H₃₈Cl₂N₈O₄
Molecular Weight	705.63
Solubility	Soluble in DMSO ≥5mg/mL(Need ultrasonic or Water bath)
Purity	HPLC≥98%
Appearance	White to yellow Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 617-596-9
MDL	MFCD00870168
SMILES	ClC1=C(C=CC(Cl)=C1)[C@@]2(O[C@@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6C(C)CC)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7
InChIKey	VHVPQPYKVGDNFY-UHFFFAOYSA-N
InChI	InChI=1S/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3
PubChem CID	55283
Target Point	Fungal;Cytochrome P450;Hedgehog
Passage	Hedgehog;Stem Cells;Metabolic Enzyme&Protease;Anti-infection
Background	It is a triazole antifungal compound and a potent Hedgehog signaling pathway antagonist. It can effectively inhibit lanosterol 14α-demethylase (Cytochrome P450), thereby inhibiting the oxidative conversion of lanosterol to ergosterol. Has anticancer and antiangiogenic activity.
Unit	Bottle
Specification	100mg 10mM*1mL in DMSO

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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