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Isoalantolactone

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Cat.No：II0160 Solarbio

CAS：470-17-7

Molecular Formula：C₁₅H₂₀O₂

Molecular Weight：232.32

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to off-white Solid

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Product Information

CAS	470-17-7
Name	Isoalantolactone
Molecular Formula	C₁₅H₂₀O₂
Molecular Weight	232.32
Solubility	Soluble in DMSO
Purity	HPLC≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
MDL	MFCD00056777
SMILES	O=C(O[C@@](C[C@@]1(C)CCC2)([H])[C@]3([H])C[C@@]1([H])C2=C)C3=C
InChIKey	CVUANYCQTOGILD-QVHKTLOISA-N
InChI	InChI=1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h11-13H,1-2,4-8H2,3H3/t11-,12+,13-,15-/m1/s1
PubChem CID	73285
Target Point	Apoptosis
Passage	Apoptosis
Background	Isoalantolactone is an alkylating agent used as an inducer of apoptosis.
Biological Activity	Isoalantolactone 是一种烷化剂，用作细胞凋亡诱导剂。[1-2]
Data Literature Source	[1]. Lawrence NJ， et al. Cytotoxic Michael-type amine adducts of alpha-methylene lactones alantolactone and isoalantolactone. Bioorg Med Chem Lett. 2001 Feb 12; 11 (3) :429-31. [2]. Khan M， et al. Isoalantolactone induces reactive oxygen species mediated apoptosis in pancreatic carcinoma PANC-1 cells. Int J Biol Sci. 2012; 8 (4) :533-47.
Unit	Bottle
Specification	10mg 10mM*1mL in DMSO 50mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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