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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > Ginsenoside Rh2CAS：78214-33-2
Molecular Formula：C36H62O8
Molecular Weight：622.87
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 78214-33-2 |
| Name | Ginsenoside Rh2 |
| Molecular Formula | C36H62O8 |
| Molecular Weight | 622.87 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00800712 |
| SMILES | C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O[C@]([C@@H]([C@@H](O)[C@@H]4O)O)([H])O[C@@H]4CO)C)(CC[C@@]2([H])C3(C)C)[C@]5([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC5)C |
| InChIKey | CKUVNOCSBYYHIS-IRFFNABBSA-N |
| InChI | InChI=1S/C36H62O8/c1-20(2)10-9-14-36(8,42)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(32(3,4)24(33)12-17-34(25,35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36-/m0/s1 |
| PubChem CID | 119307 |
| Target Point | Caspase |
| Passage | Apoptosis |
| Background | Ginsenoside Rh2 induces caspase-8 and caspase-9 activation. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-pathway manner. |
| Biological Activity | Ginsenoside Rh2 是从 Ginseng 根中分离出来的。Ginsenoside Rh2 诱导 caspase-8 和 caspase-9 活化。Ginsenoside Rh2 以多途径方式诱导癌细胞凋亡。[1-2] |
| Data Literature Source | [1]. Guo XX，et al. p53-dependent Fas expression is critical for Ginsenoside Rh2 triggered caspase-8 activation in HeLa cells. Protein Cell. 2014 Mar;5(3):224-34. [2]. Wang M，et al. Ginsenoside Rh2 enhances the antitumor immunological response of a melanoma mice model. Oncol Lett. 2017 Feb;13(2):681-685. |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 20mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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The Molecular Mechanism of Ginsenoside Analogs Activating TMEM16A
Click to check >>Author：Guo S; Chen YF; Shi S; Pang CL; Wang XZ; Zhang HL;
IF：3.4000
Publish_to：Biophys J
PMID：31818463
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