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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > Ginsenoside Rg1CAS：22427-39-0
Molecular Formula：C42H72O14
Molecular Weight：801.01
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to yellow Solid
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| CAS | 22427-39-0 |
| Name | Ginsenoside Rg1 |
| Molecular Formula | C42H72O14 |
| Molecular Weight | 801.01 |
| Solubility | Soluble in DMSO ≥8mg/mL;Soluble in Ethanol ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 244-989-9 |
| MDL | MFCD00210293 |
| SMILES | [H][C@]12C(C)(C)[C@@H](O)CC[C@]1(C)[C@]3([H])[C@@]([C@@](CC[C@]4([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)(C)[C@]4([H])[C@H](O)C3)(C)C[C@@H]2O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O |
| InChIKey | YURJSTAIMNSZAE-HHNZYBFYSA-N |
| InChI | InChI=1S/C42H72O14/c1-20(2)10-9-13-42(8,56-37-34(52)32(50)30(48)25(19-44)55-37)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36+,37-,39+,40+,41+,42-/m0/s1 |
| PubChem CID | 441923 |
| Target Point | Amyloid-β |
| Passage | Neuronal Signaling |
| Background | Works by reducing Aβ levels in the brain. Ginsenoside Rg1 reduces NF-κB nuclear translocation. |
| Biological Activity | Ginsenoside Rg1 是人参的主要活性成分之一。Ginsenoside Rg1 通过降低大脑 Aβ 水平来发挥作用。Ginsenoside Rg1 减少 NF-κB 核易位。[1-3] |
| Data Literature Source | [1]. Li N，et al. A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer's disease. J Ginseng Res. 2016 Jan;40(1):9-17. [2]. Zhang L，et al. Ginsenoside Rg1 attenuates adjuvant-induced arthritis in rats via modulation of PPAR-γ/NF-κB signal pathway. Oncotarget. 2017 Jul 24;8(33):55384-55393. [3]. Wang P，et al. Effect of ginsenoside Rg1 on proliferation and differentiation of human dental pulp cells in vitro. Aust Dent J. 2012 Jun;57(2):157-65 |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Xue L, et al. J Oncol. 2022 Dec 3;2022:6184631.
Xue L, et al. J Oncol. 2022 Dec 3;2022:6184631.
Xue L, et al. J Oncol. 2022 Dec 3;2022:6184631.
Sorry, there is no more information.
Ginsenoside Rg1 Inhibits High Glucose-Induced Proliferation; Migration; and Angiogenesis in Retinal Endothelial Cells by Regulating the lncRNA SNHG7/miR-2116-5p/SIRT3 Axis
Click to check >>Author：Xue L; Hu M; Li J; Li Y; Zhu Q; Zhou G; Zhang X; Z
IF：4.5010
Publish_to：J Oncol
PMID：36510610
Ginsenoside Rg1 Inhibits STAT3 Expression by miR-15b-5p to Attenuate Lung Injury in Mice with Type 2 Diabetes Mellitus-Associated Pulmonary Tuberculosis
Click to check >>Author：Ma T; Mao X; Meng X; Wang Q
IF：2.6500
Publish_to：Evid Based Complement Alternat Med
PMID：36248428
Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis
Click to check >>Author：WangT;GaoY;YueR;WangX;ShiY;XuJ;WuB;LiY
IF：2.4000
Publish_to：Evid Based Complement Alternat Med
PMID：33133213
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