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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > Ginsenoside Rb2CAS：11021-13-9
Molecular Formula：C53H90O22
Molecular Weight：1079.28
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 11021-13-9 |
| Name | Ginsenoside Rb2 |
| Molecular Formula | C53H90O22 |
| Molecular Weight | 1079.28 |
| Solubility | Soluble in Water/DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 234-251-4 |
| MDL | MFCD00221755 |
| SMILES | C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O[C@@](O[C@H](CO)[C@@H](O)[C@@H]4O)([H])[C@@H]4O[C@]([C@@H]([C@@H](O)[C@@H]5O)O)([H])O[C@@H]5CO)C)(CC[C@@]2([H])C3(C)C)[C@]6([C@@]1([H])[C@]([C@@](CC/C=C(C)/C)(C)O[C@@H]([C@@H]([C@@H](O)[C@@H]7O)O)O[C@@H]7CO[C@H](OC[C@H](O)[C@@H]8O)[C@@H]8O)([H])CC6)C |
| InChIKey | NODILNFGTFIURN-GZPRDHCNSA-N |
| InChI | InChI=1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-69-45-41(65)34(58)26(57)21-68-45)24-11-16-52(7)33(24)25(56)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)36(60)28(20-55)71-48)74-46-42(66)38(62)35(59)27(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3/t24-,25+,26-,27+,28+,29+,30-,31+,32-,33-,34-,35+,36+,37+,38-,39-,40-,41+,42+,43+,44+,45-,46-,47-,48-,50-,51+,52+,53-/m0/s1 |
| PubChem CID | 6917976 |
| Target Point | GPR120 |
| Passage | GPCR & G Protein |
| Background | Ginsenoside Rb2 can up-regulate GPR120 gene expression. |
| Biological Activity | Ginsenoside Rb2 是人参提取物的主要生物活性成分之一。Ginsenoside Rb2 可以上调 GPR120 基因表达。[1-2] |
| Data Literature Source | [1]. Huang Q，et al. Ginsenoside Rb2 enhances the anti-inflammatory effect of ω-3 fatty acid in LPS-stimulated RAW264.7 macrophages by upregulating GPR120 expression. Acta Pharmacol Sin. 2017 Feb;38(2):192-200. [2]. Yang H，et al. Ginsenoside-Rb2and 20(S)-Ginsenoside-Rg3 from Koreanred ginseng prevent rotavirus infection in newborn mice. J Microbiol Biotechnol. 2018 Jan 11. |
| Unit | Bottle |
| Specification | 5mg 10mg 10mM*1mL in DMSO |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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The Molecular Mechanism of Ginsenoside Analogs Activating TMEM16A
Click to check >>Author：Guo S; Chen YF; Shi S; Pang CL; Wang XZ; Zhang HL;
IF：3.4000
Publish_to：Biophys J
PMID：31818463
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