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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > GeniposideCAS：24512-63-8
Molecular Formula：C17H24O10
Molecular Weight：388.37
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 24512-63-8 |
| Name | Geniposide |
| Molecular Formula | C17H24O10 |
| Molecular Weight | 388.37 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD16036219 |
| SMILES | O[C@@H]1[C@@H](CO)O[C@@H](O[C@H]2[C@@]3([H])[C@@](CC=C3CO)([H])C(C(OC)=O)=CO2)[C@H](O)[C@H]1O |
| InChIKey | IBFYXTRXDNAPMM-BVTMAQQCSA-N |
| InChI | InChI=1S/C17H24O10/c1-24-15(23)9-6-25-16(11-7(4-18)2-3-8(9)11)27-17-14(22)13(21)12(20)10(5-19)26-17/h2,6,8,10-14,16-22H,3-5H2,1H3/t8-,10-,11-,12-,13+,14-,16+,17+/m1/s1 |
| PubChem CID | 107848 |
| Target Point | Others |
| Passage | Others |
| Background | It is an iridoid glycoside with various biological activities. |
| Biological Activity | Geniposide具有多种生物活性，例如抗糖尿病，抗氧化，抗增殖和神经保护活性。[1-4] |
| Data Literature Source | [1]. Liu H， et al. Fructus Gardenia (Gardenia jasminoides J. Ellis) phytochemistry， pharmacology ofcardiovascular， and safety with the perspective of new drugs development. J Asian Nat Prod Res. 2013; 15 (1) :94-110. [2]. Li F， et al. Geniposide attenuates inflammatory response by suppressing P2Y14 receptor and downstream ERK1/2 signaling pathway in oxygen and glucose deprivation-induced brain microvascular endothelial cells. J Ethnopharmacol. 2016 Jun 5; 185:77-86. [3]. Wu SY， et al. Effect of geniposide， a hypoglycemic glucoside， on hepatic regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin. Acta Pharmacol Sin. 2009 Feb; 30 (2) :202-8. [4]. Wang J， et al. Geniposide protects against acute alcohol-induced liver injury in mice via up-regulating the expression of the main antioxidant enzymes. Can J Physiol Pharmacol. 2015 Apr; 93 (4) :261-7. |
| Unit | Bottle |
| Specification | 10mM*1mL in DMSO 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
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Network pharmacology identification of mechanisms of cerebral ischemia injury amelioration by Baicalin and Geniposide
Click to check >>Author：Wu J. Wang B. Li M. Shi YH. Wang C. Kang YG
IF：4.1200
Publish_to：Eur J Pharmacol
PMID：31229537
Potential Involvement of Organic Anion Transporters in Drug Interactions with Shuganning Injection,a Traditional Chinese Patent Medicine
Click to check >>Author：Yajuan Bi, Yanchao Xing, Chunshan Gui, Yiqing Tian, Mingzhe Zhang, Yao Yao, Ge Hu, Lifeng Han, Feng He, Youcai Zhang
IF：3.0070
Publish_to：PLANTA MEDICA
PMID：37236232
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