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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > 2-Deoxy-D-glucoseCAS：154-17-6
Molecular Formula：C6H12O5
Molecular Weight：164.16
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 154-17-6 |
| Name | 2-Deoxy-D-glucose |
| Molecular Formula | C6H12O5 |
| Molecular Weight | 164.16 |
| Solubility | Soluble in Water ≥250mg/mL;Soluble in DMSO ≥2mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 205-823-0 |
| MDL | MFCD00151328 |
| SMILES | OC1O[C@@H]([C@@H](O)[C@H](O)C1)CO |
| InChIKey | VRYALKFFQXWPIH-PBXRRBTRSA-N |
| InChI | InChI=1S/C6H12O5/c7-2-1-4(9)6(11)5(10)3-8/h2,4-6,8-11H,1,3H2/t4-,5-,6+/m1/s1 |
| PubChem CID | 108223 |
| Target Point | Hexokinase |
| Passage | Metabolic Enzyme&Protease |
| Background | It is a glucose analog, an inhibitor of glucose metabolism, and inhibits glycolysis by acting on hexokinase. |
| Biological Activity | 2-Deoxy-D-glucose 是一种葡萄糖类似物，为葡萄糖代谢抑制剂，通过作用于己糖激酶 (hexokinase) 来抑制糖酵解。[1-3] |
| Data Literature Source | [1]. Zhu Z， et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1; 65 (15) :7023-30. [2]. Ueyama A， et al. Nonradioisotope assay of glucose uptake activity in rat skeletal muscle using enzymatic measurement of 2-deoxyglucose 6-phosphate in vitro and in vivo. Biol Signals Recept. 2000 Sep-Oct; 9 (5) :267-74. [3]. Miwa H， et al. Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose. Oncol Rep. 2013 May; 29 (5) :2053-7. |
| Unit | Bottle |
| Specification | 500mg 10mM*1mL in DMSO 10mM*1mL in Water 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
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