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My CartCAS：103060-53-3
Molecular Formula：C72H101N17O26
Molecular Weight：1620.67
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥97%
Appearance：Light yellow to yellow Solid
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| CAS | 103060-53-3 |
| Name | Daptomycin |
| Molecular Formula | C72H101N17O26 |
| Molecular Weight | 1620.67 |
| Solubility | Soluble in Water/DMSO |
| Purity | ≥97% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 600-389-2 |
| MDL | MFCD08282794 |
| SMILES | O=C(N[C@H](CC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@H](C(NCC(N[C@H](C(N[C@@](C(N[C@@H](C(N[C@H]1CC(O)=O)=O)C)=O)([H])CC(O)=O)=O)CCCN)=O)=O)[C@H](OC([C@](NC([C@](NC([C@@](NC(CNC1=O)=O)([H])CO)=O)([H])[C@H](C)CC(O)=O)=O)([H])CC(C(C=CC=C2)=C2N)=O)=O)C)=O)=O)[C@@H](NC(CCCCCCCCC)=O)CC3=CNC4=CC=CC=C34 |
| InChIKey | DOAKLVKFURWEDJ-RWDRXURGSA-N |
| InChI | InChI=1S/C72H101N17O26/c1-5-6-7-8-9-10-11-22-53(93)81-44(25-38-31-76-42-20-15-13-17-39(38)42)66(108)84-45(27-52(75)92)67(109)86-48(30-59(102)103)68(110)89-61-37(4)115-72(114)49(26-51(91)40-18-12-14-19-41(40)74)87-71(113)60(35(2)24-56(96)97)88-69(111)50(34-90)82-55(95)32-77-63(105)46(28-57(98)99)83-62(104)36(3)79-65(107)47(29-58(100)101)85-64(106)43(21-16-23-73)80-54(94)33-78-70(61)112/h12-15,17-20,31,35-37,43-50,60-61,76,90H,5-11,16,21-30,32-34,73-74H2,1-4H3,(H2,75,92)(H,77,105)(H,78,112)(H,79,107)(H,80,94)(H,81,93)(H,82,95)(H,83,104)(H,84,108)(H,85,106)(H,86,109)(H,87,113)(H,88,111)(H,89,110)(H,96,97)(H,98,99)(H,100,101)(H,102,103)/t35-,36-,37-,43+,44+,45+,46+,47+,48+,49+,50-,60+,61+/m1/s1 |
| PubChem CID | 16134395 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | It is a cyclic lipopeptide antibiotic, which mainly has a strong bacteriostatic effect on Gram-positive cocci. It achieves antibacterial effects by destroying the function of bacterial cell membranes in many ways, including disrupting the transport of amino acids by the cell membrane, thereby hindering bacterial cell wall peptides. Biosynthesis of glycans and muramates, altering cell membrane potential. |
| Biological Activity | Daptomycin 是一种脂肽类抗生素，具有体外快速杀除革兰氏阳性细菌的活性。[1-3] |
| Data Literature Source | [1]. Benson CA，et al. Comparative in-vitro activity of LY146032 a new peptolide，with vancomycin and eight other agents against gram-positive organisms. J Antimicrob Chemother. 1987 Aug;20(2):191-6. [2]. Miniter PM，et al. Activity of LY146032 in vitro and in experimental enterococcal pyelonephritis. Antimicrob Agents Chemother. 1987 Aug;31(8):1199-203. [3]. Allen NE，et al. Inhibition of peptidoglycan biosynthesis in gram-positive bacteria by LY146032. Antimicrob Agents Chemother. 1987 Jul;31(7):1093-9. |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in DMSO 10mM*1mL in Water 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Antibiotic-affinity chromatographic test strip for quantitative analysis and antibiotic resistance testing of Staphylococcus aureus
Click to check >>Author：Shi Y. Yang H. He Y. Fu Z
IF：12.5820
Publish_to：Talanta
PMID：31450481
Antibiotic-affinity chromatographic test strip for quantitative analysis and antibiotic resistance testing of Staphylococcus aureus.
Click to check >>Author：Shi Y; Yang H; He Y; Fu Z.
IF：5.7560
Publish_to：Talanta
PMID：31450481
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