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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > BaicalinCAS：21967-41-9
Molecular Formula：C21H18O11
Molecular Weight：446.37
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 21967-41-9 |
| Name | Baicalin |
| Molecular Formula | C21H18O11 |
| Molecular Weight | 446.37 |
| Solubility | Soluble in DMSO ≥25mg/mL |
| Purity | HPLC≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 606-866-1 |
| MDL | MFCD00134418 |
| SMILES | O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=C(O)C(O)=C3C(C=C(C4=CC=CC=C4)OC3=C2)=O |
| InChIKey | IKIIZLYTISPENI-ZFORQUDYSA-N |
| InChI | InChI=1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1 |
| PubChem CID | 64982 |
| Target Point | NF-kB |
| Passage | NF-κB |
| Background | Baicalin is a flavonoid with significant biological activity and strong anticancer activity, which can reduce NF-κB expression. |
| Biological Activity | Baicalin 是一种从 Scutellaria baicalensis 中分离出来的类黄酮糖苷。Baicalin 降低 NF-κB 表达。[1-2] |
| Data Literature Source | [1]. Lin M，et al. The protective effect of Baicalin against renal ischemia-reperfusion injury through inhibition of inflammation and apoptosis. BMC Complement Altern Med. 2014 Jan 13;14:19. [2]. Ju XN，et al. Baicalin protects against thrombin induced cell injury in SH-SY5Y cells. Int J Clin Exp Pathol. 2015 Nov 1;8(11):14021-7 |
| Unit | Bottle |
| Specification | 10mg 10mM*1mL in DMSO 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Zhao L, Xiong M, Liu Y. J Obstet Gynaecol Res. 2021 Sep;47(9):3060-3070.
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Network pharmacology identification of mechanisms of cerebral ischemia injury amelioration by Baicalin and Geniposide
Click to check >>Author：Wu J. Wang B. Li M. Shi YH. Wang C. Kang YG
IF：4.1200
Publish_to：Eur J Pharmacol
PMID：31229537
Baicalin enhances the proliferation and invasion of trophoblasts and suppresses vascular endothelial damage by modulating long non-coding RNA NEAT1/miRNA-205-5p in hypertensive disorder complicating pregnancy
Click to check >>Author：Zhao L; Xiong M; Liu Y
IF：1.6970
Publish_to：J Obstet Gynaecol Res
PMID：34101306
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