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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > ArtemisininCAS：63968-64-9
Molecular Formula：C15H22O5
Molecular Weight：282.33
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 63968-64-9 |
| Name | Artemisinin |
| Molecular Formula | C15H22O5 |
| Molecular Weight | 282.33 |
| Solubility | Soluble in DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 1806241-263-5 |
| MDL | MFCD00081057 |
| SMILES | O=C1[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1 |
| InChIKey | BLUAFEHZUWYNDE-NNWCWBAJSA-N |
| InChI | InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1 |
| PubChem CID | 68827 |
| Target Point | Others |
| Passage | Others |
| Background | Artemisin is a sesquiterpene lactone with anti malaria activity. Artemisin can reduce the proliferation, migration, invasion, tumorigenesis and metastasis of cancer cells, and also has neuroprotective activities. |
| Biological Activity | Artemisinin (also known as qinghaosu in Chinese), discovered by Tu Youyou (2015 Nobel Prize winner in Medicine), is an anti-malarial drug isolated from the aerial parts of Artemisia annua L. plants. Artemisinin and its semi-synthetic derivatives are a group of drugs that possess the most rapid action of all current drugs against Plasmodium falciparum malaria.[6] |
| Data Literature Source | [1]. Zeng Z，et al. Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway. Redox Biol. 2017 Apr 4;12:625-633. [2]. Chekhun VF，et al. Artemisinin modulating effect on human breast cancer cell lines with different sensitivity to cytostatics. Exp Oncol. 2017 Mar;39(1):25-29. [3]. Xu G，et al. Neuroprotective effects of artemisinin against isoflurane-induced cognitive impairments and neuronal cell death involve JNK/ERK1/2 signalling and improved hippocampal histone acetylation in neonatal rats. J Pharm Pharmacol. 2017 Mar 12. [4]. Obeid S，et al. Artemisinin analogues as potent inhibitors of in vitro hepatitis C virus replication. PLoS One. 2013 Dec 11;8(12):e81783. [5]. Wang HY，et al. The effects of artemisinin on the proliferation and apoptosis of vascular smooth muscle cells of rats. Cell Biochem Funct. 2013 Sep 17. [6]. Redox Biol. 2017 Apr 4;12:625-633. |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in DMSO 200mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Computational and Experimental Studies Reveal That Thymoquinone Blocks the Entry of Coronaviruses Into In Vitro Cells
Click to check >>Author：Xu H; Liu B; Xiao Z; Zhou M; Ge L; Jia F; Liu Y; J
IF：5.4000
Publish_to：Infectious Diseases and Therapy
PMID：33532909
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