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Aripiprazole

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Cat.No：IA0500 Solarbio

CAS：129722-12-9

Molecular Formula：C₂₃H₂₇Cl₂N₃O₂

Molecular Weight：448.39

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to yellow Solid

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Product Information

CAS	129722-12-9
Name	Aripiprazole
Molecular Formula	C₂₃H₂₇Cl₂N₃O₂
Molecular Weight	448.39
Solubility	Soluble in DMSO
Purity	HPLC≥98%
Appearance	White to yellow Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 200-835-2
MDL	MFCD00892072
SMILES	O=C1NC2=C(C=CC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CC3)=C2)CC1
InChIKey	CEUORZQYGODEFX-UHFFFAOYSA-N
InChI	InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)
PubChem CID	60795
Target Point	5-HT Receptor
Passage	Neuronal Signaling;GPCR & G Protein
Background	It is reported to be a high-affinity 5-HT receptor partial agonist.
Biological Activity	Aripiprazole (OPC-14597) is a novel atypical antipsychotic drug that is reported to be a high-affinity 5-HT receptor partial agonist.[1-2]
IC50	5-HT1A:4.2nM(Ki) [1]
Data Literature Source	[1] Burris KD，et al. J Pharmacol Exp Ther，2002，302(1)，381-389. [2] Shapiro DA，et al. Neuropsychopharmacology，2003，28(8)，1400-1411. [3] Keller RK，et al. Biochem Biophys Res Commun，1999，266(2)，560-563. [4] Li Z，et al. Eur J Pharmacol，2004，493(1-3)，75-83.
Unit	Bottle
Specification	100mg 10mM*1mL in DMSO 200mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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